Topic 36
Organic
Synthesis
Topic 36 at A Level (and its AS twin, Topic 21) asks you to identify the functional groups in a molecule with several groups and predict its properties and reactions (36.1.1), to devise multi-step synthetic routes using the reactions in the syllabus (36.1.2), and to analyse a given route for the type of reaction and reagents at each step and its possible by-products (36.1.3). The chirality of drug molecules in synthesis (29.4.4) is taught with route planning, and the pages gather the analytical, carbon-chain and practical skills a synthesis question draws on.
Revision Notes
6 revision notes, in the order the specification teaches them.
Deducing Formulae from Analytical Data
Deducing empirical, molecular and structural formulae from percentage composition and spectra.
Start revisingIdentifying Functional Groups by Chemical Tests
Identifying functional groups by chemical tests and predicting the properties and reactions of unfamiliar compounds.
Start revisingCarbon–Carbon Bond Formation
Forming carbon–carbon bonds in synthesis: the nitrile routes from haloalkanes and carbonyl compounds.
Start revisingPlanning a Synthetic Route
Planning multi-step organic synthesis routes: the reaction map, working backwards from the target.
Start revisingPreparing and Purifying Organic Solids
Preparing and purifying organic solids: reflux, filtration, recrystallisation, drying and melting temperature determination.
Start revisingPurifying Liquids and Checking Purity
Purifying organic liquids: distillation, solvent extraction, drying and checking purity.
Start revisingSummary Map
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Summary map
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Aromatic and Multi-Step Synthesis Map
Cambridge International AS & A Level Chemistry · Topic 36 Organic synthesis
All of Topic 36 on one A4 page: several groups, aromatic and multi-step routes, and analysing a route for by-products.
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Specification
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36.1.1
36.1.2
- 36.1.2
devise multi-step synthetic routes for preparing organic molecules using the reactions in the syllabus
Revise
36.1.3
- a
analyse a given synthetic route in terms of type of reaction and reagents used for each step of it
Revise
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